We'll focus on leveraging large-scale visualization and large tiled displays to enable scientific discovery. We'll present a case study where domain scientists evaluate the complicated, hierarchical microstructure of enamel in primate teeth to gain insight into the principles governing the evolution of mineralized biological tissues. We integrate X-ray micro-tomography with large-scale visualization and analysis techniques to explore the internal structure of mineralized biological tissues. In an interactive visualization session, we'll bring domain scientists and visualization experts together to collaborate. We'll explore a high-resolution visualization streaming from a GPU-based visualization cluster on a large tiled display, along with a distributed global illumination algorithm, which helps scientists improve depth perception in rendered images. Analyzing the data interactively, domain scientists are able to identify structures previously unseen in the data.