Le Lu has served as a staff scientist since 2013 in the Department of Radiology and Imaging Sciences, National Institutes of Health Clinical Center, Bethesda, Maryland. His research is focused on medical image understanding and semantic parsing to fit into new clinical practices, especially in the areas of preventive early cancer detection/diagnosis and developing precise novel imaging bio-markers, via large-scale imaging protocols and statistical (deep) learning principles. Le worked on various core R&D problems in colonic polyp and lung nodule CADx systems, and vessel, bone imaging at Siemens Corporate Research and Siemens Healthcare from 2006 to 2013, and his last post was a senior staff scientist. He has been named on 18 U.S. and international patents and is the inventor or co-inventor of 32 inventions. Le has authored over 90 peer-reviewed papers. He received his Ph.D. in computer science from Johns Hopkins University in 2007. He won the Mentor of the Year award in the staff scientist/clinician category.